Effects of methyl isocyanate on rat brain cells in culture.
نویسندگان
چکیده
Since the disaster in Bhopal, India, people exposed to methyl isocyanate (MIC) have complained of various disorders including neuromuscular dysfunction. In an attempt to get information about such dysfunction we have previously shown that MIC can affect muscle cells in culture. The present communication reports investigations into the effect of MIC on brain cells in culture. MIC was toxic to brain cells and the response was dose related. The observations were supported by light and electron microscopy.
منابع مشابه
Effects of methyl isocyanate on rat muscle cells in culture.
Since the Bhopal disaster, in which the causal agent was methyl isocyanate (MIC), exposed people have complained of various disorders including neuromuscular dysfunction. In an attempt to gain some information about the response of muscle tissue to MIC its effects were investigated in cells in culture isolated from muscle of 2 day old rats. After treatment with a range of MIC concentrations (0....
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ورودعنوان ژورنال:
- British journal of industrial medicine
دوره 47 9 شماره
صفحات -
تاریخ انتشار 1990